Download e-book for kindle: Adhesion Molecules (Modern Insights Into Disease from by Victor R. Preedy

By Victor R. Preedy

ISBN-10: 157808671X

ISBN-13: 9781578086719

This ebook covers the constitution and category of adhesion molecules in terms of signaling pathways and gene expression. It discusses immunohistochemical localization, neutrophil migration, and junctional, useful, and inflammatory adhesion molecules in pathologies comparable to leukocyte decompression disorder and ischemia reperfusion damage. Highlighting the clinical functions of present examine, chapters disguise diabetes, weight problems, and metabolic syndrome; hypoxia; kidney illness; smoking, atrial traumatic inflammation, and center disorder, the mind and dementia; and tumor proliferation. eventually, it seems at molecular imaging and bioinformatics, high-throughput applied sciences, and chemotherapy.

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Additional resources for Adhesion Molecules (Modern Insights Into Disease from Molecules to Man)

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B: Membrane-bound JAM-A exists as dimer. Dimerization is mediated through a dimerization motif in the first Ig-like domain which is conserved in JAM-A, -B and -C. C: JAM dimers undergo trans-homophilic interactions. JAMs REGULATE LEUKOCYTE-ENDOTHELIAL CELL INTERACTIONS DURING INFLAMMATION The role of our immune system is to detect and eliminate pathogens or selfmodified components from the body. Cells of the innate immune system recognize pathogens or self-modified components, which results in the eradication of the foreign agent at the site of injury or in the initiation of the adaptive immune response mediated by T and B cells in the draining secondary lymphoid organs.

2004. Structural basis for dimerization of ICAM-1 on the cell surface. Mol. Cell. 14: 269-276. P. and T. Stehle, B. Diefenbach, R. Zhang, R. L. Scott, A. L. A. Arnaout. 2001. Crystal structure of the extracellular segment of integrin alpha V beta 3. Science 294: 339-345. indd 21 CHAPTER 2 Immunohistochemical Localization of Adhesion Molecules H. Wayne Sampson1,* and Alan R. , Department of Systems Biology and Translational Medicine, Texas A&M Health Science Center College of Medicine, 336 Joe H.

Cells of the innate immune system recognize pathogens or self-modified components, which results in the eradication of the foreign agent at the site of injury or in the initiation of the adaptive immune response mediated by T and B cells in the draining secondary lymphoid organs. Indeed, tissue macrophages or dendritic cells take up antigens in the periphery and migrate to lymph nodes in which they present antigens to T cells. This evolutionary strategy has succeeded because the immune system has co-developed the structures necessary to communicate between blood, tissues and lymph nodes, namely vascular and lymphatic systems.

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Adhesion Molecules (Modern Insights Into Disease from Molecules to Man) by Victor R. Preedy


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