Download PDF by Hai Hu, Michael Liebman: Biomedical Informatics in Translational Research

By Hai Hu, Michael Liebman

ISBN-10: 1596930381

ISBN-13: 9781596930384

Not anyone is worked up that it takes 10 years for a drug to arrive the marketplace, yet now eventually there's a new new release of analysis instruments which can support lower time-consuming hindrances all the way down to dimension. This trail-blazing source on biomedical informatics offers researchers with leading edge suggestions for integrating and federating information from scientific and molecular reviews. those equipment increase info assortment, monitoring, garage, visualization, research, and information discovery tactics, and permit researchers to translate wisdom from "bench to bedside" and "bedside to bench" with never-before pace and potency. whole with examples demonstrating tips on how to strengthen instruments for particular biomedical informatics initiatives, this quantity can assist all scientific researchers deal with facts, expedite their efforts, and utilize special uncomplicated examine.

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Extra resources for Biomedical Informatics in Translational Research

Example text

So far, the company has isolated genes believed to be involved in cardiovascular disease and cancer [10]. , target identification or validation) require more in-depth associated clinical data, such as medical and family histories, treatment, and clinical outcomes data. All data collected must be entered into the repository’s biomedical informatics system, where it can be integrated with data from the genomics and proteomics research platforms. Uniform, approved protocols must be used to enroll donors and obtain biospecimens.

To protect patient confidentiality and to comply with federal patient privacy regulations, all clinical samples collected for research should be deidentified. Deidentified samples are those that have had all identifiers or codes removed such that the ability to identify particular individuals, via clinical or demographic information, would be extremely difficult for the researcher. The deidentification process starts first with the patient, who should be assigned a unique patient-specific research number, and continues with the data collection forms and clinical samples.

Multiple questionnaires containing clinical data are collected on each patient and biospecimens are, thus, extensively annotated. Researchers use the repository to conduct proteomic and genomic research. Clinical data are analyzed in response to proteomic and genomic analysis and findings. Biomedical informatics scientists develop informatics structures and expand the informatics environment on which the research relies for rapid translation into the clinical environment. Given the challenges of adequately describing research with many goals in easy-to-understand language, the section of the informed consent document used by the CBCP that describes the study is two pages long.

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Biomedical Informatics in Translational Research by Hai Hu, Michael Liebman

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