By Ricardo V. Lloyd MD, PhD (auth.)
Endocrine Pathology integrates classical diagnostic anatomic pathology with contemporary advancements in immunochemistry and molecular biology in its method of endocrine problems. The e-book discusses not just quite a lot of illnesses regularly encountered in daily scientific perform but in addition these unusual stipulations elucidated by means of such cutting edge innovations as ultrastructural immunochemistry and in situ hybridization.
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Additional info for Endocrine Pathology
Microscopically, the simple goiters usually have large follicles lined by flattened epithelium and distended with colloid (Fig. 10). Multinodular goiters have a variegated appearance. Some areas show distended follicles lined by flattened epithelium, while other areas may have hyperplastic follicles. 1). Microscopic evidence of retrogressive changes, including hemosiderin-laden macrophages, calcification fibrosis, and cholesterol clefts in areas of old and recent hemorrhage, is often present. 9.
Circulating autoantibodies are seen in up to 80% of patients. It may represent the end stage of autoimmune thyroiditis in which a goiter was absent or went unnoticed (36). The gland is small and consists mostly of fibrous tissue with occasional thyroid follicles and lymphocytic infiltrates. Thyroiditis Inflammatory diseases affecting the thyroid can range from severe conditions such as Hashimoto's thyroiditis and subacute thyroiditis to lesions such as thyroiditis of pregnancy. 40 3. 3. Gross appearance of thyroid in Hashimoto's thyroiditis (A).
Virchows Arch [Pathol Anat] 395:59-68 32. Kovacs K, Horvath E, Ryan N, Ezrin C (1980) Null cell adenoma ofthe human pituitary. Virchows Arch [Pathol Anat] 387:165-174 33. Kovacs K, Horvath E, Stratmann IE, Ezrin C (1974) Cytoplasmic microfIlaments in the anterior lobe of the human pituitary gland. Acta Anat (Basel) 87: 414-426 34. Kovacs K, Lloyd RV, Horvath E, Asa SL, Stefaneanu L, Killinger DW, Smyth HS (1989) Silent somatotroph adenomas of the human pituitary. A morphologic study ofthree cases including immunocytochemistry, electron microscopy in vitro examination and in situ hybridization.
Endocrine Pathology by Ricardo V. Lloyd MD, PhD (auth.)