By Robert J. Amdur, Ernest L. Mazzaferri
This quantity outlines sufferer care from prognosis via a variety of remedies for thyroid melanoma sufferers. It serves as a cutting-edge reference for clinicians offering finished details at the scope of this sickness, together with surgical procedure, nuclear drugs remedies, recurrence and metastases. Reference details is integrated for either physicians and thyroid melanoma sufferers.
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Additional resources for Essentials of Thyroid Cancer Management
Smanik, PA, Q Liu, TL Furminger, K Ryu, S Xing,, EL Mazzaferri, and SM Jhiang. 1996. Cloning of the human sodium iodide symporter. Biochem Biophys Res Commun 226:339–345. Van Herle, AJ, and RP Uller. 1975. Elevated serum thyroglobulin. A marker of metastases in differentiated thyroid carcinomas. J Clin Invest 56:272–277. Van Herle, AJ, G Vassart, and JE Dumont. 1979. Control of thyroglobulin synthesis and secretion (ﬁrst of two parts). N Engl J Med 301:239–249. 3. PATHOLOGY AND CLASSIFICATION OF THYROID CARCINOMA HEATHER M.
Follicular Cancer a) Classic morphology (called “Follicular Carcinoma”) - minimally invasive versus widely invasive b) Hürthle Cell variant -minimally invasive versus widely invasive B. Poorly differentiated thyroid cancer (Insular Carcinoma) C. Undifferentiated thyroid cancer (Anaplastic Carcinoma) II. THE CELL OF ORIGIN IS THE PARAFOLLICULAR C-CELL Medullary carcinoma Figure 1. Classiﬁcation of thyroid cancer based on histology. capsule is the thin layer of connective tissue that surrounds the normal thyroid gland.
Figure 7. H¨urthle cell carcinoma (200X): Hurthel cells have abundant cytoplasm that appears pink and grainy when stained with Hematoxylin and Eosin. In other locations in the body, cells with these features are called oncocytes. As in follicular thyroid tumors, malignancy in a H¨urthle cell tumor is deﬁned by invasion of tumor through the tumor capsule rather than nuclear abnormalities. 3. Pathology and Classiﬁcation of Thyroid Carcinoma 27 Figure 8. Poorly differentiated (Insular) carcinoma (100X): These tumors are thought to represent a poorly differentiated form of papillary carcinoma.
Essentials of Thyroid Cancer Management by Robert J. Amdur, Ernest L. Mazzaferri