By Stefan Dübel, Janice M. Reichert
Nonetheless the main complete reference resource at the improvement, creation and healing program of antibodies, this moment variation is punctiliously up-to-date and now has 30% extra content material.
Volume 1 covers choice and engineering concepts for brand spanking new antibodies, whereas the second one quantity provides novel healing ideas and antibodies in scientific research, in addition to their capability. Volumes three and four function special and particular information regarding every one antibody licensed for healing reasons, together with medical facts. This designated guide concludes with a compendium of advertised monoclonal antibodies and an in depth index.
Beyond offering present wisdom, the authors speak about rising applied sciences, destiny advancements, and highbrow estate concerns, such that this instruction manual meets the wishes of educational researchers, determination makers in and healthcare pros within the hospital.
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Additional resources for Handbook of Therapeutic Antibodies
I. Parren, and Ronald P. Taylor 64 Omalizumab (Xolair) – Anti-Immunoglobulin E Treatment in Allergic Diseases 1775 Claus Kroegel and Martin Foerster 65 Palivizumab (Synagis®) Louis Bont 66 Panitumumab (Vectibix®): A Treatment for Metastatic Colorectal Cancer 1855 Jonas K¨ugler 67 Pertuzumab (Perjeta®) 1871 Jose Angel Garc´ıa-Sa´enz, Fernando Moreno Anton, and Coralia Bueno Mui˜no 68 Ranibizumab (Lucentis): a New Anti-Angiogenic Treatment in Ophthalmology 1883 Nicolas Leveziel, Marc Ohresser, and Gilles Paintaud 69 Raxibacumab, Human Monoclonal Antibody against Anthrax Toxin 1899 Sally D.
2 Toll-Like Receptor Inhibitors in Phase 1 and 2 Clinical Studies for Immunological Disorders 1145 Frank R. Brennan Introduction 1145 Toll-Like Receptor Inhibitors 1146 Anti-TLR2 1146 Anti-TLR3 1147 Anti-TLR4 1149 References 1151 IgE Inhibitors in Phase 1 and 2 Clinical Studies for Immunological Disorders 1159 Frank R. Brennan Introduction 1159 IgE Inhibitors 1161 Anti-IgE 1161 Anti-IgE M1′ 1162 References 1163 Complement Inhibitors in Phase 1 and 2 Clinical Studies for Immunological Disorders 1165 Frank R.
Palestro Index 2143 V Contents Volume I: Deﬁning the Right Antibody Composition Quick Reference List of Antibodies by International Nonproprietary Name XXIII Quick Reference List of Antibodies by Brand Name XXV A Greeting by the Editors XXVII Foreword to the First Edition XXIX Foreword to the Second Edition XXXI List of Contributors XXXIII Abbreviations LI Appendix: Marketed Monoclonal Antibodies Compendium LXXXIII 1 Therapeutic Antibodies – from Past to Future Stefan D¨ubel and Janice M. Reichert 1 Part I: Selecting and Shaping the Antibody Molecule 15 2 Selection Strategies for Monoclonal Antibodies 17 Gerhard Moldenhauer 3 Antibody Phage Display 43 Michael Hust, Andr´e Frenzel, Florian Tomszak, Jonas K¨ugler, and Stefan D¨ubel 4 Transgenic Animals Derived by DNA Microinjection 77 Marianne Br¨uggemann, Michael J.
Handbook of Therapeutic Antibodies by Stefan Dübel, Janice M. Reichert