Alan R. Saltiel, Jeffrey E. Pessin's Mechanisms of insulin action PDF

By Alan R. Saltiel, Jeffrey E. Pessin

ISBN-10: 0387722033

ISBN-13: 9780387722030

More than 18 million humans within the usa have diabetes mellitus, and approximately ninety% of those have the sort 2 kind of the affliction. additionally, among 17 and forty million humans have insulin resistance, impaired glucose tolerance, or the cluster of abnormalities observed variably because the metabolic syndrome, the dysmetabolic syndrome, syndrome X, or the insulin resistance syndrome. In all of those problems, a significant part of the pathophysiology is insulin resistance, i.e., diminished responsiveness to insulin in tissues reminiscent of muscle, fats and liver. Insulin resistance can be heavily associated with different universal illnesses, together with weight problems, polycystic ovarian affliction, hyperlipidemia, high blood pressure, and atherosclerosis. during this booklet, we'll try and dissect the complexity of the molecular mechanisms of insulin motion with a unique emphasis on these positive factors of the process which are topic to alteration in variety 2 diabetes and different insulin resistant states. We discover insulin motion on the most simple degrees, via advanced structures. The ebook should be beautiful to uncomplicated and medical scientists.

Show description

Read or Download Mechanisms of insulin action PDF

Best endocrinology & metabolism books

Read e-book online Cardiovascular Endocrinology:: Shared Pathways and Clinical PDF

Over the last few a long time, heart problems and diabetes have emerged as significant public illnesses, either as targeted medical entities and as comorbid stipulations. therefore, the fields of vascular biology and endocrinology are operating extra heavily now than ever prior to. With chapters via popular specialists, Cardiovascular Endocrinology: Shared Pathways and scientific Crossroads emphasizes the huge physiological interrelationships and medical correlations among the specialties of cardiovascular medication and endocrinology.

Nutritional Aspects of Osteoporosis - download pdf or read online

This booklet is predicated on shows given on the 5th foreign Symposium on dietary points of Osteoporosis held in Lausanne, Switzerland in 2003. even supposing a regularly overlooked bankruptcy of clinical study, the dietary affects on bone overall healthiness was once a mentioned subject at this congress. additionally mentioned have been new insights into the position of proteins, supplements, potassium, greens, meals acid load, mineral waters and calcium.

Download PDF by Icon Health Publications: The Official Patient's Sourcebook on Multiple Endocrine

This booklet has been created for sufferers who've determined to make schooling and learn an essential component of the remedy strategy. even though it additionally provides info priceless to medical professionals, caregivers and different healthiness execs, it tells sufferers the place and the way to seem for info masking almost all issues relating to a number of endocrine neoplasia style 1 (also hyperparathyroidism; MEN1; Sipple's syndrome; Wermer's syndrome), from the necessities to the main complicated parts of study.

Get Endocrine Disruptors and Puberty PDF

Endocrine disruption represents the most debatable environmental problems with our time. Mounting facts stemming from greater than 10 years of experimental, epidemiological and medical reviews has reworked the as soon as more often than not discounted topic of endocrine disruptors into a subject matter of great hindrance not just in the medical neighborhood yet between society as an entire.

Additional info for Mechanisms of insulin action

Sample text

Whole-genome shotgun assembly and analysis of the genome of Fugu rubripes. Science 2002; 297:1301-1310. 46. Scavo L, Shuldiner AR, Serrano J et al. Genes encoding receptors for insulin and insulin-like growth factor I are expressed in Xenopus oocytes and embryos. Proc Nad Acad Sci USA 1991; 88:6214-6218. 47. Hainaut P, Kowalski A, Giorgetti S et al. Insulin and insulin-like-growth-factor-I (IGF-I) receptors in Xenopus laevis oocytes. Comparison with insulin receptors from liver and muscle. Biochem J 1991; 273:673-678.

In: De Groot L, Jameson LJ, eds. Endocrinology. 4th ed. Philadelphia: WB Saunders Co, 2001:25-47. 224. Loren CE, Englund C, Grabbe C et al. A crucial role for the Anaplastic lymphoma kinase receptor tyrosine kinase in gut development in Drosophila melanogaster. EMBO Rep 2003; 4:781-786. 225. Robinson DR, Wu YM, Lin SF. The protein tyrosine kinase family of the human genome. Oncogene 2000; 19:5548-5557. 226. Ogiso H, Ishitani R, Nureki O et al. Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains.

FuUbright G, Lacy ER, BuUesbach EE. The prothoracicotropic hormone bombyxin has specific receptors on insect ovarian cells. Eur J Biochem 1997; 245:774-780. 21. Graf R, Neuenschwander S, Brown MR et al. Insulin-mediated secretion of ecdysteroids fi"om mosquito ovaries and molecular cloning of the insulin receptor homologue from ovaries of bloodfed Aedes aegypti. Insect Mol Biol 1997; 6:151-163. 22. Holt RA, Subramanian GM, Halpern A et al. The genome sequence of the malaria mosquito Anopheles gambiae.

Download PDF sample

Mechanisms of insulin action by Alan R. Saltiel, Jeffrey E. Pessin

by Kevin

Rated 4.81 of 5 – based on 11 votes