By Andrew J. Krentz, Nathan D. Wong
Addressing a subject matter of extreme significance within the box, this article addresses the epidemiology, analysis, overview, and administration of sufferers with metabolic syndrome-focusing on implications for heart problems possibility. With an abundance of in actual fact equipped tables, flowcharts, and perform instructions, this blue-ribbon resource succinctly analyzes contemporary scientific trials, compares and assesses contemporary and rising cures, and gives strategies for the enhanced evaluation and therapy of sufferers, whereas providing a cutting-edge evaluation of methods to optimize and improve sufferer care.
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Extra info for Metabolic syndrome and cardiovascular disease : epidemiology, assessment, and management
Hu G, Qiao Q, Tuomilehto J, et al. Prevalence of the metabolic syndrome and its relation to all–cause and cardiovascular mortality in nondiabetic European men and women. Arch Intern Med 2004; 164:1066–1076. 31. Last JM, ed. A Dictionary of Epidemiology. 3rd ed. New York: Oxford University Press, 1995:180. 32. Hodge AM, Boyko EJ, de Courten M, et al. Leptin and other components of the metabolic syndrome in Mauritius: a factor analysis. Int J Obes Relat Metab Disord 2001; 25:126–131. 33. Meigs JB, D’Agostino RB, Wilson PFW, Cupples LA, Nathan DM, Singer DE.
The metabolic syndrome: is this diagnosis necessary? Am J Clin Nutr 2006; 83:1237–1247 DK9373_Krentz_Ch01 9/28/06 6:37 PM Page 13 Metabolic Syndrome: Nomenclature, Definition, and Diagnosis 13 3. Kylin E. Studien ueber das Hypertonie-Hyperglyka “mie-Hyperurika” miessyndrom. Zentralblatt fuer Innere Medizin 1923; 44:105–127 4. Maranon G. “Pradiabetische Zustande”. Abhandlungen aus den grenzgebiete der Inneren Secretion. Wisenschafthliche Verlags Buchhandlung Rudolf Novak & C. Budapest Leipzig 1927:12–42.
A dysfunctional endothelium is thought to be one of the earliest events in atherogenesis. Clinically, this is detectable by a loss of or reduction in vasodilator function, though other endothelial functions including the capacity to act as selective barrier are also affected. Endothelial dysfunction is likely to be important at all the stages of atherogenesis right through to the advanced disease and acute plaque events. A large body of evidence has been established linking clinical measures of endothelial dysfunction and risk of vascular events.
Metabolic syndrome and cardiovascular disease : epidemiology, assessment, and management by Andrew J. Krentz, Nathan D. Wong