By Arnost Kleinzeller, Felix Bronner
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Additional resources for Molecular Approaches to Epithelial Transport
Puhl. ) 614, 157-160. Nagel. W. (1977). The dependence of the electrical potentials across the membranes of the frog skin upon the concentration of sodium in the mucosal solution. J . Physiol. (London) 269, 777-796. Neumcke, B. (1982). Fluctuation of Na and K currents in excitable membranes. l n t . Rev. Neurobiol. 23, 35-67. Palmer, L. G . , Li, J. , Lindemann. , and Edelman, I . S . (1982). Aldosterone control of the density of sodium channels in the toad urinary bladder. J . Membr. B i d . 64, 91-102.
L - c d area of skin from R . 8, 1 phf amiloride. The spontaneous open circuit potential was -64 mV. The open circles show that the comer frequency was independent of clamp level, whereas the current and plateau values increased with increasing clamp levels. include an additive amiloride-insensitive component. By examining a log-log plot it should be possible to deduce the power dependence between the plateau and the current. If the noise were true shot noise and the current fluctuations were due movement of quanta1 units of charge, the plateau should be proportional to the first power of the current, independently of the driving force.
VI. Conclusions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . I. 11. I. 27 29 29 29 31 32 36 40 45 45 INTRODUCTION The conductive and capacitive (polarizable) properties of cell membranes are normally described by means of a resistance R and a capacitance C, which are interconnected by the time constant T = R . C of charging in response to a square wave constant-current pulse.
Molecular Approaches to Epithelial Transport by Arnost Kleinzeller, Felix Bronner