By E. Pannese
During the second one half the 20 th century, the creation of various new concepts vastly extended our wisdom of the constitution of nerve and neuroglial cells and of the association of the worried method on the mobile point. This new details has, besides the fact that, quite often been scattered through the literature, making it tough for investigators to achieve an total imaginative and prescient of the self-discipline. the writer has marshalled those scattered facts to supply a scientific assessment of the sector positioned inside of a historic context. He has correlated the key new findings with the classical notions of sunshine microscopy and has built-in them with components of biochemistry and mobile body structure. After the book of the 1st variation, the advent of latest microscopies and particularly the expansion of molecular biology have tremendously multiplied our wisdom, particularly at the intercellular communique within the frightened process and at the roles of neuroglial cells. those achievements have made a moment variation of the ebook worthwhile. The absolutely revised and up to date textual content, including detailed high quality illustrations of buildings of the vital and peripheral apprehensive approach, make sure that this re-creation can be useful for neuroscientists, fairly these desirous about mobile neuropathology, neurochemistry, neurophysiology and molecular neurobiology.
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Additional resources for Neurocytology: Fine Structure of Neurons, Nerve Processes, and Neuroglial Cells
Here, therefore, a list of the most common types of neuron, distinguished by the characteristics of their processes, is given. Most nerve cells in vertebrates have several dendrites but only one axon. These multipolar neurons correspond well to the typical nerve cell so often referred to when describing the nerve cell in a general way. Golgi (1882) distinguished two types of multipolar neuron on the basis of the configuration of the axon. The axon of type I cells sends out few collateral branches, retaining its distinct identity, and becomes myelinated.
Lipofuscin granules are the best known example of residual bodies. These pigment granules, which range from 1 to 3 μm in diameter, appear as golden brown particles in unstained preparations examined with the light microscope and exhibit autofluorescence in ultraviolet light; they stain with Sudan black and are positive after staining with the periodic acid-Schiff reagent. When observed under the electron microscope (Figs. 10), lipofuscin granules appear as irregularly shaped, membrane-bounded bodies which exhibit a complex structure (Hess 1955); they consist of a dense, granular material, membranous arrays, and one or more homogeneous, spherical vacuoles of low density, which are often peripherally placed (Samorajski et al.
5 μm in diameter, appear as dark brown particles in unstained preparations examined under the light microscope. They do not stain with the periodic acid-Schiff reagent, 48 do not autofluoresce in ultraviolet light, and are both argentaffin and argyrophilic. When observed under the electron microscope, neuromelanin granules show some structural similarities to lipofuscin granules.
Neurocytology: Fine Structure of Neurons, Nerve Processes, and Neuroglial Cells by E. Pannese