Download e-book for iPad: The Management of Obesity and Related Disorders by Peter G Kopelman MD FRCP

By Peter G Kopelman MD FRCP

ISBN-10: 0203213130

ISBN-13: 9780203213131

ISBN-10: 0203291301

ISBN-13: 9780203291306

ISBN-10: 1853179140

ISBN-13: 9781853179143

Administration of weight problems and similar problems concentrates at the administration, pharmacological and differently, of weight problems and its comparable difficulties. Diabetes, cardiovascular and respiration problems, hyperlipidemia and fibrinolytic abnormalities are all exacerbated by means of weight problems, that's now epidemic in scale. Professor Peter Kopelman has assembled a global staff of specialists to debate the matter of weight problems and its similar issues. the 1st part of this useful consultant discusses the various administration methods of workout, vitamin, habit, pharmacology and surgical procedure, whereas the second one part concentrates at the administration of the categorical similar problems.

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Example text

If the oral treatment fails, insulin therapy may be prescribed, alone or in combination with oral agents. 10 Those who oppose the use of sulphonylureas often argue that sulphonylurea treatment could be counterproductive because it may lead to weight gain, hyperinsulinaemia and even more severe insulin resistance, all effects which are particularly unwanted in obese subjects. It is essential that this series of events be kept in mind whenever sulphonylurea therapy is started and that every effort is made to prevent it.

However, it is obvious that the most effective way to improve the prognosis of obese patients is to obtain sustained weight loss. Further studies are necessary to improve the identification of good responders to pharmacotherapy and to specify the role of anti-obesity agents in the overall long-term 36 Obesity and diabetes management of obese subjects with type 2 diabetes. The management of the obese diabetic patient should combine strategies which aim at reducing weight excess, lowering chronic hyperglycaemia and correcting other risk factors.

107 Groop LC, Sulfonylureas and NIDDM, Diabetes Care (1992) 15:737–54. 108 Lebovitz HE, Melander A, Sulfonylureas: basic aspects and clinical uses. In: Alberti KGMM, Zimmet P, DeFronzo RA, Keen H, eds, International Textbook of Diabetes Mellitus, 2nd edn (J Wiley: Chichester, 1997) 817–40. 109 United Kingdom Prospective Diabetes Study Group, United Kingdom Prospective Diabetes Study Group 24: A 6-year, randomized, controlled trial comparing sulfonylurea, insulin, and metformin therapy in patients with newly diagnosed type 2 diabetes that could not be controlled with diet therapy, Ann Intern Med (1998) 128:165–75.

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The Management of Obesity and Related Disorders by Peter G Kopelman MD FRCP


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