Type 2 Diabetes Mellitus: An Evidence-Based Approach to by Mark N. Feinglos, Mary Angelyn Bethel PDF

By Mark N. Feinglos, Mary Angelyn Bethel

ISBN-10: 1588297942

ISBN-13: 9781588297945

During this functional e-book, the authors of every bankruptcy have synthesized the at present on hand facts concerning particular concerns in diabetes care. The chapters were written by way of an interdisciplinary workforce of scientists and doctors. Such an strategy emphasizes the necessity for collaboration within the care of anybody with diabetes and within the attempt to discover new treatments for the ailment. This reference presents functional assistance in one source.

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Additional resources for Type 2 Diabetes Mellitus: An Evidence-Based Approach to Practical Management (Contemporary Endocrinology)

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That found essentially a 100% concordance rate (9). However, this kind of study provides no insight into the underlying genetic defect (s) either directly impairing the glucose homeostasis system or causing insulin resistance or another defect that exceeds the capacity of a normal glucose homeostasis system. With the advent of molecular biology, the basis is now known for many monogenic forms of diabetes, such as mitochondrial genome defects and their association with diabetes and deafness (10), Wolfram’s syndrome (11), several syndromes of extreme insulin resistance (12), and most of the MODY syndromes (13).

This review provides an overview of the current understanding of the pathogenesis of type 2 diabetes (Fig. 1). A major focus of the proposed sequence relates to defects in the mass and function of islet ß-cells, as they are known to be important elements in the early stages of the disease. K. that found essentially a 100% concordance rate (9). However, this kind of study provides no insight into the underlying genetic defect (s) either directly impairing the glucose homeostasis system or causing insulin resistance or another defect that exceeds the capacity of a normal glucose homeostasis system.

2005;353:1454–1462. 63. Weir GC. Non-insulin-dependent diabetes mellitus: interplay between B-cell inadequacy and insulin resistance. Am J Med 1982;73:461–464. 64. Buchanan TA, Xiang AH, Peters RK, et al. Preservation of pancreatic beta-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk hispanic women. Diabetes 2002;51:2796–2803. 65. Xiang AH, Peters RK, Kjos SL, et al. Effect of pioglitazone on pancreatic beta-cell function and diabetes risk in Hispanic women with prior gestational diabetes.

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Type 2 Diabetes Mellitus: An Evidence-Based Approach to Practical Management (Contemporary Endocrinology) by Mark N. Feinglos, Mary Angelyn Bethel


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